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Search Results for " oxidative damage "

20

Compounds

Cat No. Product Name Synonyms Targets
T5116 Iprodione Others , Reactive Oxygen Species , Antifungal
Iprodione is a fungicide. Iprodione is also used in cannabis testing kits as a component of pesticide mixes.
TN2100 Pratensein Others , NF-κB
Pratensein as a novel transcriptional up-regulator of scavenger receptor class B type I in HepG2 cells.
T5669 Citric acid monohydrate Others
Citric Acid Monohydrate is a tricarboxylic acid found in citrus fruits. Citric acid is used as an excipient in pharmaceutical preparations due to its antioxidant properties. It maintains stability of active ingredients a...
T5S0636 Citric acid Citro,Citretten Apoptosis , Others , Endogenous Metabolite , Antibacterial , Antibiotic
1. Citric acid (Citro) (1-2 g/kg) can decrease brain lipid peroxidation and inflammation, liver damage, and DNA fragmentation. 2. Citric acid denture cleansers can reduce C. albicans biofilm accumulation and cell viabili...
T14042 4-P-PDOT 4-phenyl-2- propionamidotetralin Melatonin Receptor , MT Receptor
4-P-PDOT (4-phenyl-2- propionamidotetralin) is a potent, selective and affinity Melatonin receptor (MT2) antagonist.
T40192 DGTP 2'-Deoxyguanosine-5'-triphosphate Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis
dGTP (2'-Deoxyguanosine-5'-triphosphate) is one of the guanosine nucleotides which is highly susceptible to oxidative damage to 8-O-GDP, 8-O-dGTP, 8-O-GTP, and 8-O-dGTP.
T20793 Magnesium Lithospermate B Monomethyl lithospermate B,Lithospermate B Others
Magnesium Lithospermate B is a natural product activates eNOS and ameliorates endothelial dysfunction in diabetes by enhancing vasodilation in addition to reducing oxidative stress, it can protecte cardiomyocytes from is...
T2S2003 Phlorizin dihydrate Phloridzin dihydrate Others
1. Phlorizin dihydrate (Phloridzin dihydrate) can significantly inhibit oxidative DNA damage.
T19165 8-Hydroxyguanine 8 Hydroxyguanine,7,8-dihydro-8-oxoguanine,2-Amino-6,8-dihydroxypurine Endogenous Metabolite
8-Hydroxyguanine (8 Hydroxyguanine) is the major premutagenic damage produced by reactive oxygen species. It causes G-T and A-C substitutions.8-Hydroxyguanine is a biomarker for RNA oxidation and oxidative DNA damage.8-H...
T8177 Galactinol Others
Galactinol Hydrate scavenges hydroxyl free radicals and protects plant cells from oxidative damage.
T12059L Mitoquinone mesylate MitoQ mesylate,MitoQ10 mesylate Reactive Oxygen Species
Mitoquinone mesylate (MitoQ10 mesylate) is a TPP-based, mitochondrially targeted antioxidant to protect against oxidative damage.
T1710 Trolox Apoptosis , Antioxidant , Ferroptosis , Reactive Oxygen Species
Trolox is a vitamin E analogue, used in reducing oxidative stress or damage.
TN1461 (-)-Butin Butin Akt , PI3K , Nrf2
(-)-Butin (Butin) has antioxidant activity, can protect cells against H2O2-induced apoptosis, oxidative DNA damage and oxidative mitochondrial dysfunction; it attenuates oxidative stress by activating Nrf2-mediated Mn SO...
TQ0154 8-Hydroxyguanosine Others , Endogenous Metabolite
8-hydroxyguanosine (8-OHG) is a marker for measuring the rate of oxidative damage to nucleic acids and lipids.
T68182L 3-Hydroxykynurenamine HCl 3-OH-Kynurenamine HCl,3-Hydroxykynurenamine HCl(99362-47-7 Free base) Others
3-Hydroxykynurenamine HCl (3-OH-Kynurenamine HCl) is an immunomodulatory biogenic amine, an intermediate in the catabolism of amino acids, which induces oxidative damage and promotes cell death.
T4890 3-Nitro-L-tyrosine 3-Nitrotyrosine Endogenous Metabolite
3-Nitro-L-tyrosine (3-Nitrotyrosine) is the major product from the spontaneous reaction of peroxynitrite with tyrosine. Formation of nitrotyrosine can indicate the formation of peroxynitrite by a nitric oxide (NO)-depend...
TN1043 Keracyanin chloride Cyanidin-3-O-rutinoside chloride,Cyanidin 3-rutinoside chloride,Cyanidin 3-O-rutinoside chloride COX
Keracyanin chloride (Cyanidin 3-rutinoside chloride), an anthocyanin compound, exhibits antioxidant properties. It effectively prevents the formation of malonaldehyde in oxidized calf thymus DNA, underlining its potentia...
T1695 DL-O-Tyrosine Amino Acids and Derivatives
DL-o-Tyrosine is a metabolite of Phenylalanine and is a precursor in the formation of catecholamines. It is used as biomarkers of protein oxidative damage in β-thalassemia.
T3671 Vitexin-2"-O-rhamnoside 2''-O-Rhamnosylvitexin,Vitexin-2-O-rhaMnoside,Vitexin-2''-O-rhamnoside,Apigenin-8-C-glucoside Others
Vitexin-2"-O-rhamnoside (Apigenin-8-C-glucoside) is a compound contributes to the protection against H O -mediated oxidative stress damage.
T3S1068 Oxyresveratrol trans-Oxyresveratrol,2,3',4,5'-tetrahydroxystilbene,Tetrahydroxystilbene Tyrosinase , Autophagy , HSV
1. Oxyresveratro can inhibit tyrosinase activity. 2. Oxyresveratro is useful to trauma models, as toxicity to glia could be beneficial by inhibiting reactive gliosis. 3. Oxyresveratrol (trans-Oxyresveratrol) has antioxid...

Compounds

Iprodione
T5116
Synonym:
Target: Others, Reactive Oxygen Species, Antifungal
Pratensein
TN2100
Synonym:
Target: Others, NF-κB
Citric acid monohydrate
T5669
Synonym:
Target: Others
Citric acid
T5S0636
Synonym: Citro,Citretten
Target: Apoptosis, Others, Endogenous Metabolite, Antibacterial, Antibiotic
4-P-PDOT
T14042
Synonym: 4-phenyl-2- propionamidotetralin
Target: Melatonin Receptor, MT Receptor
dGTP
T40192
Synonym: 2'-Deoxyguanosine-5'-triphosphate
Target: Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis
Magnesium Lithospermate B
T20793
Synonym: Monomethyl lithospermate B,Lithospermate B
Target: Others
Phlorizin dihydrate
T2S2003
Synonym: Phloridzin dihydrate
Target: Others
8-Hydroxyguanine
T19165
Synonym: 8 Hydroxyguanine,7,8-dihydro-8-oxoguanine,2-Amino-6,8-dihydroxypurine
Target: Endogenous Metabolite
Galactinol
T8177
Synonym:
Target: Others
Mitoquinone mesylate
T12059L
Synonym: MitoQ mesylate,MitoQ10 mesylate
Target: Reactive Oxygen Species
Trolox
T1710
Synonym:
Target: Apoptosis, Antioxidant, Ferroptosis, Reactive Oxygen Species
(-)-Butin
TN1461
Synonym: Butin
Target: Akt, PI3K, Nrf2
8-Hydroxyguanosine
TQ0154
Synonym:
Target: Others, Endogenous Metabolite
3-Hydroxykynurenamine HCl
T68182L
Synonym: 3-OH-Kynurenamine HCl,3-Hydroxykynurenamine HCl(99362-47-7 Free base)
Target: Others
3-Nitro-L-tyrosine
T4890
Synonym: 3-Nitrotyrosine
Target: Endogenous Metabolite
Keracyanin chloride
TN1043
Synonym: Cyanidin-3-O-rutinoside chloride,Cyanidin 3-rutinoside chloride,Cyanidin 3-O-rutinoside chloride
Target: COX
DL-O-Tyrosine
T1695
Synonym:
Target: Amino Acids and Derivatives
Vitexin-2"-O-rhamnoside
T3671
Synonym: 2''-O-Rhamnosylvitexin,Vitexin-2-O-rhaMnoside,Vitexin-2''-O-rhamnoside,Apigenin-8-C-glucoside
Target: Others
Oxyresveratrol
T3S1068
Synonym: trans-Oxyresveratrol,2,3',4,5'-tetrahydroxystilbene,Tetrahydroxystilbene
Target: Tyrosinase, Autophagy, HSV
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TargetMol